Native Americans were the first to use cranberries for their medicinal properties. Cranberries were used for a variety of complaints, including blood disorders, stomach ailments, liver problems, and fever.
Urinary tract infections are caused by microorganisms, mainly Gram-negative bacteria. Indeed, Escherichia coli (E. coli) account for most cases. Treatment usually involves antibio-tics, and recurrence is a major concern.
Traditionally, cranberry juice has been used for the treatment and prophylaxis of urinary tract infections. Cranberry appears to be a safe, herbal choice for UTI prophylaxis and has relatively good tolerability.
The UTI prevention mechanism of cranberry juice is related to anti-adhesive properties of proanthocyanidins and fructose, which work against adhesion molecules of E. coli. These compounds inhibit the adherence of E. coli to tissues, thereby preventing infection.
Cranberry juice for treatment and prevention of urinary tract infection 
